Over Reacting to an Absence of PINK

Two genes when mutated, PINK1 and PARKIN, are associated with young onset Parkinson's. Exactly why they increase the risk of developing Parkinson's has long been a mystery, but now Canadian scientists have published research that might be able to explain this increased susceptibility... Read more

From Dreams to Parkinson's

Professor Michele Hu has published an interesting article providing an overview of the 'prodromal phase' or the period before diagnosis in Parkinson's... Read more

The Appendix and Parkinson's

Although its exact role isn’t yet clear because findings have been conflicting, in this easy-to-read overview the link between the appendix and risk of developing Parkinson's is discussed... Read more

The Rationale for the TRANSEURO Study

The TRANSEURO study is being funded by The Cure Parkinson's Trust and is investigating cell transplantation as a restorative therapy for people with Parkinson's. In this article, Prof Roger Barker explains the rational behind the trial design... Read more

Not Easy for EGCG

Disappointing results for Epigallocatechin-gallate (EGCG) as study fails to show evidence of modifying disease progression in patients with Multiple System Atrophy. Read more

Research that has Gone to the Dogs

It is hoped that Parkinson's detecting dogs will be able to help with early detection of Parkinson's, aid in the diagnosis and improve our understanding the condition. Read more

New Drug to Target Alpha-Synuclein

Scientists are to develop a drug which blocks the enzyme which prevents the natural breakdown of the toxic protein alpha-synuclein... Read more

Hilton Food Group's Third Annual Charity Golf Day

The Cure Parkinson’s Trust were delighted to be one of beneficiary charities of the Hilton Food Group’s third annual charity golf day, held at Hanbury Manor on the 6th June. Read more

More Evidence that Parkinson's Originates in the Gut

A new study published in the journal Neuron has found more evidence that Parkinson's starts in cells in the gut and journeys to the brain via the body's neurons. Read more

The Behaviours of Alpha-Synuclein

Researchers are beginning to better understand the behaviours of the alpha-synuclein protein implicated in Parkinson's. In this article, Linked Clinical Trials committee member David Sulzer discusses the findings... Read more

Could Changes in the Levels of Serotonin Signal Parkinson's?

Researchers from King's College London have uncovered the earliest signs of Parkinson's in the brain, long before any symptoms are evident. The results could potentially lead to screening tools for identifying people at greatest risk - an important area of research interest... Read more

CuATSM - A Promising Compound

Following on from interesting results in a clinical trial of motor neurone disease earlier this year this new study in Parkinson's further supports the potential utility of this compound... Read more

Anle-138b - New Research Suggests Neuroprotection

Recently published new research by UK scientists - supported by The Cure Parkinson's Trust - suggest a new treatment that breaks down toxic protein aggregates could be neuroprotective in Parkinson's... Read more

Webinar - Stem Cell (Cell Replacement) Therapy

Our recent webinar (June 2019) discusses developments in the field of stem cell therapy for Parkinson's. Watch now... Read more

The Mike Tindall Celebrity Golf Classic 2019

Celebrity guests joined Mike Tindall MBE and his wife, Zara, for the Celebrity Golf Classic held at The Belfry with funds raised going to CPT's research... Read more

The AEGIS Coast to Coast to Cure Challenge

13 supporters of The Cure Parkinson’s Trust (CPT), including CPT Patron Mike Tindall MBE and fellow Rugby World Cup winner Iain Balshaw MBE, completed the historic 'Raid Pyrenean last month to raise vital funds for CPT’s search for a cure for Parkinson’s. Read more

The 'Coast To Coast To Cure' Endurance Cycle

This week AEGIS London and The Cure Parkinson’s Trust (CPT) hosted a Q&A event with rugby legends Mike Tindall and Iain Balshaw to talk about Parkinson’s, CPT’s ground-breaking research and the extreme Coast to Coast to Cure Challenge... Read more

World Parkinson Congress, Kyoto: 4-7 June 2019

This triennial congress provides an international forum for dialogue on the latest scientific discoveries, medical practices, and caregiver initiatives related to Parkinson’s disease... Read more

Early Indication that NAC May Improve Dopamine Function in Parkinson's

Investigators at Thomas Jefferson University, Philadelphia have reported that in a study of 42 patients, those who received N-acetyl cyteine (NAC) experienced a significant lessening of the motor and non-motor symptoms. The results suggest that NAC may positively affect the dopaminergic system in people with Parkinson's, with corresponding positive clinical effects. Read more

'Cooling' Inflamed Brains in Parkinson's

When cells in the body become unwell or injured, they release proteins that inform the body of their stricken situation. These activate the release of further signalling proteins called inflammasomes... Read more

GDNF Gene Therapy Clinical Trial

At the recent annual American Association of Neurological Surgeons meeting, researchers presented the results of a Phase I clinical trial designed to test the safety and tolerability of a gene therapy approach for GDNF in Parkinson's. Read more