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The Cure Parkinson's Trust

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  • The AZA-PD study: a clinical trial of azathioprine in Parkinson's

    The AZA-PD study: a clinical trial of azathioprine in Parkinson's

    A research group in Cambridge - supported by The Cure Parkinson's Trust and Cambridge Centre for Parkinson-Plus - will be conducting a clinical trial to test whether suppressing the immune system can help to slow the progression of Parkinson's. Read more

  • The 2020 Tom Isaacs Charity Golf Days

    The 2020 Tom Isaacs Charity Golf Days

    We were thrilled to still be able to host the 2020 Tom Isaacs Charity Golf Day this year. Team members were invited to enjoy a round of golf in memory of The Cure Parkinson’s Trust’s late co-founder and President Tom Isaacs. Read more

  • The Cure Parkinson's 2021 Raid Series

    The Cure Parkinson's 2021 Raid Series

    Following the immense success last year’s Raid Pyrenean and this year’s virtual Raid Local event, we are excited to announce the Cure Parkinson’s 2021 Raid Series. Read more

  • CPT Awarded the Lloyd’s Market Charity Award 2020

    CPT Awarded the Lloyd’s Market Charity Award 2020

    The Cure Parkinson’s Trust are delighted to be the recipient of the 2020 Lloyd’s Market Charity Award receiving a £25,000 donation in support of our pioneering research into a cure for Parkinson’s. Read more

  • The AZA-PD study: a clinical trial of azathioprine in Parkinson's
  • The 2020 Tom Isaacs Charity Golf Days
  • The Cure Parkinson's 2021 Raid Series
  • CPT Awarded the Lloyd’s Market Charity Award 2020
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  1. News & events
  2. News

News

The AZA-PD study: a clinical trial of azathioprine in Parkinson's

The AZA-PD study: a clinical trial of azathioprine in Parkinson's

A research group in Cambridge - supported by The Cure Parkinson's Trust and Cambridge Centre for Parkinson-Plus - will be conducting a clinical trial to test whether suppressing the immune system can help to slow the progression of Parkinson's. Read more

Published: 1st December, 2020

Author: Suzanne Bailey

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The 2020 Gulls' Eggs and Grouse & Grape Virtual Event

The 2020 Gulls' Eggs and Grouse & Grape Virtual Event

On 18 November, two of the city’s longest-standing fundraising events, the Gulls' Eggs and the Grouse & Grape Luncheons joined forces to deliver a brilliant virtual event raising £60,000 for The Cure Parkinson’s Trust’s ground-breaking research. Read more

Published: 30th November, 2020

Author: Gemma Marks

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The 2020 Tom Isaacs Charity Golf Days

The 2020 Tom Isaacs Charity Golf Days

We were thrilled to still be able to host the 2020 Tom Isaacs Charity Golf Day this year. Team members were invited to enjoy a round of golf in memory of The Cure Parkinson’s Trust’s late co-founder and President Tom Isaacs. Read more

Published: 28th October, 2020

Updated: 29th October, 2020

Author: Gemma Marks

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The Cure Parkinson's 2021 Raid Series

The Cure Parkinson's 2021 Raid Series

Following the immense success last year’s Raid Pyrenean and this year’s virtual Raid Local event, we are excited to announce the Cure Parkinson’s 2021 Raid Series. Read more

Published: 23rd October, 2020

Author: Gemma Marks

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CPT Awarded the Lloyd’s Market Charity Award 2020

CPT Awarded the Lloyd’s Market Charity Award 2020

The Cure Parkinson’s Trust are delighted to be the recipient of the 2020 Lloyd’s Market Charity Award receiving a £25,000 donation in support of our pioneering research into a cure for Parkinson’s. Read more

Published: 14th October, 2020

Updated: 16th October, 2020

Author: Gemma Marks

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'Run Local' CPT's 7 Day Festival of Running

'Run Local' CPT's 7 Day Festival of Running

Between 4 and 11 October, over 100 of our supporters embraced their favourite local routes and took part in The Cure Parkinson’s Trust’s (CPT) ‘Run Local’ event, - our first ever 7 day festival of running in support of our research. Read more

Published: 12th October, 2020

Updated: 14th October, 2020

Author: Gemma Marks

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Paul Mayhew-Archer MBE becomes a Patron

Paul Mayhew-Archer MBE becomes a Patron

We are delighted to announce that TV writer, producer and comedian Paul Mayhew-Archer is now a patron of The Cure Parkinson’s Trust (CPT). Read more

Published: 12th October, 2020

Updated: 21st December, 2020

Author: Gemma Marks

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Type 2 Diabetes Medications Impact Risk of Parkinson’s

Type 2 Diabetes Medications Impact Risk of Parkinson’s

In a recent study supported by The Cure Parkinson's Trust, researchers concluded that the elevated risk of Parkinson’s disease in patients with type 2 diabetes might be mitigated depending on the type of drugs prescribed to treat diabetes. Read more

Published: 7th October, 2020

Updated: 12th October, 2020

Author: Suzanne Bailey

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The International Linked Clinical Trials Meeting

The International Linked Clinical Trials Meeting

In September, the annual International Linked Clinical Trials committee convened to prioritise drugs to direct through to clinical trial - over 20 world-leading Parkinson's experts reviewed a set of newly compiled drug dossiers with potential to treat Parkinson's. Read more

Published: 5th October, 2020

Updated: 4th November, 2020

Author: Gemma Marks

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Our Virtual Rallying to The Challenge Meeting – ‘When and How Does Parkinson’s Begin?’

Our Virtual Rallying to The Challenge Meeting – ‘When and How Does Parkinson’s Begin?’

For the first time, this year's meeting for people with Parkinson's, was held online and focussed on the origins and development of Parkinson’s, including triggers, early symptoms and stages of the disease. Read more

Published: 24th September, 2020

Updated: 6th October, 2020

Author: Suzanne Bailey

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Drug Shows Signs of Efficacy in Early Stage Parkinson’s

Drug Shows Signs of Efficacy in Early Stage Parkinson’s

In April the results of a major clinical trial - called the PASADENA study - were announced. Although the results indicated that the trial had not achieved a positive result based on a predetermined measure of success, the investigators conducting the study indicated that there were ‘signals of efficacy‘ in the data. Read more

Published: 21st September, 2020

Updated: 28th September, 2020

Author: Gemma Marks

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The John Black Charitable Foundation joins CPT as Strategic Funding Partner

The John Black Charitable Foundation joins CPT as Strategic Funding Partner

The Cure Parkinson’s Trust (CPT) and Van Andel Institute (VAI) are delighted to welcome a third strategic funding partner, The John Black Charitable Foundation (JBCF), to the International Linked Clinical Trials (iLCT) programme. Together, these three have pledged USD $6.75 million to Parkinson’s research, over three years. Read more

Published: 21st September, 2020

Updated: 29th September, 2020

Author: Suzanne Bailey

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The PD-STAT/Simvastatin study results

The PD-STAT/Simvastatin study results

This week the results of a large Cure Parkinson's Trust-funded clinical trial were released, evaluating the disease-modifying potential of the cholesterol-lowering drug simvastatin in people with Parkinson's. The results indicate that the treatment does not have any impact of the progression of the condition. Read more

Published: 15th September, 2020

Updated: 28th September, 2020

Author: Gemma Marks

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Cure3 Exhibition raises £1 million for The Cure Parkinson's Trust

Cure3 Exhibition raises £1 million for The Cure Parkinson's Trust

On 5 September The Cure Parkinson’s Trust (CPT) launched the 3rd edition of Cure3, an acclaimed selling exhibition devised by Artwise Curators and kindly hosted  by Bonhams, London, to raise funds and awareness of CPT’s research into a cure for Parkinson’s. Early results from Cure3 2020 confirm that this unique selling event has now raised over £1m for The Cure Parkinson’s Trust. Read more

Published: 14th September, 2020

Updated: 15th September, 2020

Author: Gemma Marks

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Cure3 2020

Cure3 2020

Cure3 2020, the third edition of the acclaimed selling exhibition, is taking place this week in support of CPT. Read more

Published: 3rd September, 2020

Updated: 15th September, 2020

Author: Gemma Marks

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Dexamethasone for COVID - and Perhaps Parkinson's?

Dexamethasone for COVID - and Perhaps Parkinson's?

A corticosteroid medication used to reduce inflammation in conditions such as arthritis and asthma has shown to help COVID-19 patients - and there is a growing body of evidence to suggest that these medications may also be useful in the treatment of Parkinson's Read more

Published: 2nd September, 2020

Updated: 3rd September, 2020

Author: Suzanne Bailey

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2020 Fundraiser of the Year Award

2020 Fundraiser of the Year Award

We are delighted to announce that the nominations for the 2020 Fundraiser of the Year Award are now open! Read more

Published: 27th August, 2020

Updated: 25th September, 2020

Author: Gemma Marks

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The Epigenetics of Parkinson's.

The Epigenetics of Parkinson's.

In their epigenetics study of Parkinson's, researchers at the Van Andel Institute (Michigan) have identified a “master regulator” gene switch that may protect the brain from neurodegeneration. Read more

Published: 19th August, 2020

Author: Suzanne Bailey

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A Biomarker for Parkinson's?

A Biomarker for Parkinson's?

A research report published this week, highlights a protein that could represent the first 'biomarker' for Parkinson's progression. Read more

Published: 19th August, 2020

Updated: 20th August, 2020

Author: Suzanne Bailey

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DENALI and Biogen Team Up Against LRRK2

DENALI and Biogen Team Up Against LRRK2

A collaborative deal between Denali and Biogen brings a new potential Parkinson's treatment a step closer. Read more

Published: 10th August, 2020

Author: Suzanne Bailey

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MODAG: Positive Phase 1 Results of Potential New Parkinson's Drug

MODAG: Positive Phase 1 Results of Potential New Parkinson's Drug

Supported by CPT, German Biotech company MODAG have announced positive results from their phase 1 clinical trial of Anle138b for Parkinson's. Read more

Published: 10th August, 2020

Author: Suzanne Bailey

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An Overview of Drug Development for Parkinson's

An Overview of Drug Development for Parkinson's

Recently published research, conducted by Parkinson's research advocates and CPT, presents an encouraging overview of current agents in the pipeline for the treatment of Parkinson's. This report represents one of the first classifications and in-depth analysis of its kind in the Parkinson's clinical trials arena Read more

Published: 5th August, 2020

Updated: 11th August, 2020

Author: Suzanne Bailey

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Helping the Research Community Restart their Studies

Helping the Research Community Restart their Studies

As researchers in the field of Parkinson’s take steps to invite patients back to take part in face-to-face studies, we'd like to hear your views about returning to participate in research in the UK. Read more

Published: 3rd August, 2020

Author: Gemma Marks

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CPT's Dr Richard Wyse Co-edits Prestigious Cochrane Report

CPT's Dr Richard Wyse Co-edits Prestigious Cochrane Report

CPT's Dr Richard Wyse is the co-editor of a recent Cochrane Report on GLP‐1 receptor agonists and their potential use in treating Parkinson's Disease Read more

Published: 30th July, 2020

Updated: 3rd August, 2020

Author: Gemma Marks

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Further Evidence of Neuroprotection of Simvastatin in Parkinson's

Further Evidence of Neuroprotection of Simvastatin in Parkinson's

Researchers in Israel have recently published an interesting new study which provides a novel insight and further independent support for simvastatin which CPT is clinically testing in people with Parkinson's. Read more

Published: 29th July, 2020

Author: Suzanne Bailey

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'Cabbages and Kings Magazine' in support of CPT

'Cabbages and Kings Magazine' in support of CPT

Long term supporters from the Leicestershire, Northamptonshire and Rutland Committee led by Meriel Buxton have produced and printed a wonderful magazine 'Cabbages and Kings' to help raise funds for CPT’s research. Read more

Published: 21st July, 2020

Updated: 23rd July, 2020

Author: Gemma Marks

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Blood Plasma Infusions for Parkinson's

Blood Plasma Infusions for Parkinson's

Research has shown that infusions of blood plasma from young animal models can improve the health of older animal models, and a recent study of plasma infusions in people with Parkinson's warrants further investigations. Read more

Published: 9th July, 2020

Author: Suzanne Bailey

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The “Raid Local” Cycle Challenge

The “Raid Local” Cycle Challenge

On Sunday 28 June, over 1000 supporters of The Cure Parkinson’s Trust (CPT) took to the saddle to take part in the charity’s “Raid Local” cycle challenge, and have - so far - raised an astonishing £250,000 (including gift aid) for CPT’s vital research into a cure for Parkinson’s. Read more

Published: 3rd July, 2020

Updated: 21st September, 2020

Author: Gemma Marks

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Parkinson's: the Absense of Appendixes & Tonsils

Parkinson's: the Absense of Appendixes & Tonsils

Recent research of large data in Sweden has shown removal of tonsils and appendixes reduces the risk of Parkinson's. Read more

Published: 1st July, 2020

Author: Suzanne Bailey

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Astrocytes to Dopamine Neurons in One Step

Astrocytes to Dopamine Neurons in One Step

A Chinese research group have shown that 'helper cells' in the brain called astrocytes can be converted to nerve cells, which then can go on to produce dopamine - the brain chemical lost in Parkinson's. This is exciting news, but further research is needed. Read more

Published: 25th June, 2020

Author: Suzanne Bailey

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Our ‘Raid Alpine’ has become ‘Raid Local’. Join us!

Our ‘Raid Alpine’ has become ‘Raid Local’. Join us!

Join CPT Patron Mike Tindall MBE and celebrity friends for the ‘Raid Local’ cycle challenge. Read more

Published: 25th June, 2020

Updated: 21st September, 2020

Author: Gemma Marks

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A Greater Role for the Parkinson's GBA Gene Protein?

A Greater Role for the Parkinson's GBA Gene Protein?

A better knowledge of variations in our DNA could not only provide insights into the underlying biology of Parkinson's but could also help us understand why we are affected differently, and how best to treat the disease. Read more

Published: 22nd June, 2020

Updated: 9th July, 2020

Author: Suzanne Bailey

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Phase 1 Results for a Parkinson's Vaccine

Phase 1 Results for a Parkinson's Vaccine

The results of a phase l trial testing a potential vaccine for Parkinson's have been published. Using the body's own immune system to start developing antibodies (immunotherapy) this potential treatment targets a toxic protein called alpha-synuclein thought to be a contributing factor in Parkinson's. Read more

Published: 22nd June, 2020

Author: Suzanne Bailey

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CPT’s Radio 4 Appeal raises over £104,000!

CPT’s Radio 4 Appeal raises over £104,000!

We are absolutely delighted to announce that our BBC Radio 4 Appeal, which aired on Sunday 12 April, has raised a staggering £104,060.75! We are humbled by the incredible generosity of all who donated in support of our vital research into a cure for Parkinson’s, particularly in these difficult times, and we would like to say a heartfelt thank you. Read more

Published: 15th June, 2020

Updated: 17th June, 2020

Author: Gemma Marks

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Nerve Growth Factors and Parkinson's

Nerve Growth Factors and Parkinson's

For some considerable time CPT has been interested in nerve growth factors or 'neurotrophic' factors for Parkinson's. GDNF, CDNF and C-CDNF are three interesting candidates and our research work within this field continues with drive and urgency. Read more

Published: 3rd June, 2020

Updated: 3rd September, 2020

Author: Suzanne Bailey

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Emergency Medical Consultant Sketches to Raise Funds

Emergency Medical Consultant Sketches to Raise Funds

Dr. Johnny Acheson is an Emergency Medical Consultant who is also living with Parkinson’s. Johnny has created sketches to fundraise and to educate about Parkinson’s and depict the humorous side of working in emergency medicine! Read more

Published: 2nd June, 2020

Updated: 16th June, 2020

Author: Suzanne Bailey

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CPT Patron Mike Tindall's Auction Fundraiser

CPT Patron Mike Tindall's Auction Fundraiser

CPT patron and Rugby World Cup winner Mike Tindall MBE organised a silent auction to support the three charities close to his heart, including The Cure Parkinson’s Trust. Read more

Published: 19th May, 2020

Updated: 3rd June, 2020

Author: Gemma Marks

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Multi-Arm Multi-Stage - a New Approach to Clinical Trials

Multi-Arm Multi-Stage - a New Approach to Clinical Trials

Dr Camille Carroll of Plymouth University, a member of our International Linked Clinical Trials (iLCT) committee, has led a group of researchers in exploring a platform for conducting Multi-Arm Multi-Stage clinical trials for Parkinson's. Read more

Published: 11th May, 2020

Author: Suzanne Bailey

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The 2.6 Challenge

The 2.6 Challenge

From Sunday the 26 April, supporters of The Cure Parkinson’s Trust came together to join the nationwide 2.6 Challenge, taking part in unique activities based around the number 2.6 or 26. Here we share some of the imaginative challenges our supporters took on. Read more

Published: 24th April, 2020

Updated: 30th April, 2020

Author: Gemma Marks

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Fox Insight Launches COVID-19 Survey

Fox Insight Launches COVID-19 Survey

At present there is little or no research being undertaken on the impact of COVID-19 on the Parkinson's community. Now, Fox Insight has stepped up to the plate to facilitate this important emerging area of research. Read more

Published: 23rd April, 2020

Updated: 6th July, 2020

Author: Suzanne Bailey

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The STEADY-PD Trial Results

The STEADY-PD Trial Results

The results of the Phase lll STEADY-PD clinical trial have now been published. Read more

Published: 2nd April, 2020

Author: Suzanne Bailey

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Further Support for the 'Repurposed' Simvastatin

Further Support for the 'Repurposed' Simvastatin

Statins are a well characterised class of medication that are used to lower cholesterol levels in the body. Evidence strongly suggests certain statins have been for use as a potential treatment for Parkinson's, this particularly applies to a statin called simvastatin Read more

Published: 1st April, 2020

Updated: 8th April, 2020

Author: Suzanne Bailey

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A Better Delivery of Dopamine

A Better Delivery of Dopamine

Lower levels of dopamine are associated with the motor symptoms of the condition - slowness and rigidity of movement. New research, led by Prof. David Devos, proposes a continuous delivery of a more stable form of dopamine directly into the brain. Read more

Published: 30th March, 2020

Author: Suzanne Bailey

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#ParkinsonsTogether

#ParkinsonsTogether

We want to hear your stories, from the Parkinson’s community, about the creative ways you are keeping safe, motivated and upbeat at home during this time... Read more

Published: 29th March, 2020

Updated: 15th April, 2020

Author: Gemma Marks

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3P: Parkinson Postdoc Program Seminars

3P: Parkinson Postdoc Program Seminars

Calling early career scientists! Feeling socially distanced? Maybe quarantined? Wondering what you can do to further your career during this time? How about presenting and discussing your research with other early career neuroscientists who are in the same boat! Read more

Published: 29th March, 2020

Updated: 7th May, 2020

Author: Suzanne Bailey

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PD Frontline

PD Frontline

Many drugs developed for Parkinson's are targeted at specific genes, such as the GBA and the LRRK2 gene. To test whether these drugs work, we need to identify people with abnormalities in these genes who can be enrolled in clinical trials. Read more

Published: 26th March, 2020

Author: Suzanne Bailey

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Time to Re-nurture Neurturin?

Time to Re-nurture Neurturin?

Results of a disappointing clinical trial in 2013 testing a gene therapy for Parkinson's have been re-investigated with some new and important implications for future trials in the field. Read more

Published: 26th March, 2020

Updated: 21st April, 2020

Author: Suzanne Bailey

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News: COVID-19

News: COVID-19

First and foremost in these difficult times we hope that everyone stays safe. This is an ongoing situation causing disruption and anxiety and CPT is monitoring and responding to the unprecedented COVID-19 crisis as it evolves. Read more

Published: 19th March, 2020

Updated: 6th July, 2020

Author: Suzanne Bailey

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Multi-Arm Multi-Stage Trials for Parkinson's

Multi-Arm Multi-Stage Trials for Parkinson's

Most clinical trials involve a single therapy, being tested against a 'placebo' or control treatment for a fixed period of time. The MAMS study technique explores a potential new trial design for Parkinson's Read more

Published: 18th March, 2020

Updated: 1st June, 2020

Author: Suzanne Bailey

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Exenatide: Further Studies Initiated

Exenatide: Further Studies Initiated

The Cure Parkinson's Trust is encouraged to see the growing field of study of exenatide in Parkinson's. Read more

Published: 18th March, 2020

Author: Suzanne Bailey

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Identifying People with Parkinson’s Best Suited to Benefit from Genetic Targeted Therapies

Identifying People with Parkinson’s Best Suited to Benefit from Genetic Targeted Therapies

CPT recently approved funding for Prof. Antony Cooper to find people with idiopathic Parkinson’s who could benefit from new therapies being developed for genetic forms of the condition, particularly GBA Parkinson's. Read more

Published: 12th March, 2020

Updated: 14th March, 2020

Author: Suzanne Bailey

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World Parkinson's Day - 11th April 2020

World Parkinson's Day - 11th April 2020

On World Parkinson's Day we are partnering with Parkinson's UK to reach out to everyone affected by Parkinson's, in a joined up effort, to support a campaign of awareness to challenge misconceptions, and help people to better understand Parkinson's. Read more

Published: 9th March, 2020

Updated: 3rd April, 2020

Author: Suzanne Bailey

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Please be Aware

Please be Aware

In light of the recent outbreak of the novel coronavirus, we are closely monitoring government advice on the situation. Read more

Published: 6th March, 2020

Updated: 12th March, 2020

Author: Gemma Marks

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Revising our Approach to Treating Parkinson's

Revising our Approach to Treating Parkinson's

The Krembil Knowledge Gaps in Parkinson's Disease Symposium addressed some of the fundamental questions for further advancing Parkinson's research. Read more

Published: 5th March, 2020

Author: Suzanne Bailey

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Herantis Pharma: Phase 1/2 CDNF Topline Results

Herantis Pharma: Phase 1/2 CDNF Topline Results

Herantis Pharma Plc have announced that their ongoing Phase 1-2 clinical trial testing the neuroprotective agent ‘cerebral dopamine neurotrophic factor’ (or CDNF) in people with Parkinson’s has met its primary endpoint Read more

Published: 26th February, 2020

Author: Suzanne Bailey

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Mercer & Hole announce CPT as 'Charity of the Year'

Mercer & Hole announce CPT as 'Charity of the Year'

The Cure Parkinson’s Trust (CPT) is delighted to have been chosen as one of Mercer and Hole’s 2020 charity partners. Read more

Published: 24th February, 2020

Updated: 5th March, 2020

Author: Gemma Marks

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Earlier Diagnosis and Treatment of Dementia in Parkinson's

Earlier Diagnosis and Treatment of Dementia in Parkinson's

Recently published research from UCL suggests monitoring of levels of iron in people with Parkinson's may help with early diagnosis and earlier treatment of dementia Read more

Published: 24th February, 2020

Updated: 27th February, 2020

Author: Suzanne Bailey

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GDNF and Cell Transplantation: Dual therapies for Parkinson's

GDNF and Cell Transplantation: Dual therapies for Parkinson's

Scientists in Australia have recently published pre-clinical research exploring multiple treatment approaches for Parkinson's, in particular using GDNF alongside cell replacement therapy. Read more

Published: 20th February, 2020

Updated: 26th February, 2020

Author: Suzanne Bailey

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The Minnesota UDCA Clinical Study

The Minnesota UDCA Clinical Study

Recently, researchers in Minnesota (USA) published the results of a small pilot clinical trial investigating the safety of Ursodeoxycholic acid (or UDCA) in Parkinson's. Read more

Published: 20th February, 2020

Updated: 25th February, 2020

Author: Suzanne Bailey

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UDCA and Laboratory Cell-Based Parkinson's

UDCA and Laboratory Cell-Based Parkinson's

Researchers at Sheffield and Oxford Universities have recently published research exploring 'subtypes' of Parkinson's in cell-culture studies, which has highlighted a drug that The Cure Parkinson's Trust is clinically testing. Read more

Published: 20th February, 2020

Updated: 25th February, 2020

Author: Suzanne Bailey

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Similarities between Alzheimer's and Parkinson's

Similarities between Alzheimer's and Parkinson's

Two groups recently published independent journal articles suggesting that a genetic variation associated with Alzheimer's might also have an important influence in Parkinson's. Read more

Published: 13th February, 2020

Author: Suzanne Bailey

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AEGIS Office2Office Ride 2020

AEGIS Office2Office Ride 2020

This September, AEGIS London will be taking on the Castel Office2Office Ride, cycling from London to Amsterdam raising funds and awareness for The Cure Parkinson's Trust. Read more

Published: 13th February, 2020

Updated: 25th February, 2020

Author: Gemma Marks

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A Sub-Study Investigating Azathioprine in Parkinson's

A Sub-Study Investigating Azathioprine in Parkinson's

In Parkinson’s there appears to be an over-abundance of inflammatory cells in the brain. This study will examine how azathioprine impacts this inflammation to determine whether this drug could be a future treatment for Parkinson's. Read more

Published: 11th February, 2020

Author: Suzanne Bailey

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New Developments In Diabetes Drugs for Parkinson's

New Developments In Diabetes Drugs for Parkinson's

At the forefront of treatments for diabetes is a class of drug called glucagon-like peptide 1 receptor (GLP-1R) agonists. There is now considerable evidence that suggest GLP-1R diabetes drugs could potentially be used in the treatment of Parkinson's. Read more

Published: 30th January, 2020

Updated: 12th February, 2020

Author: Suzanne Bailey

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Martin Wishart Sails the Atlantic for The Cure Parkinson's Trust

Martin Wishart Sails the Atlantic for The Cure Parkinson's Trust

Scottish Michelin Star Chef Martin Wishart recently completed his incredible challenge of sailing 3,500 miles across the Atlantic, raising a phenomenal £69,000 for The Cure Parkinson’s Trust. Read more

Published: 15th January, 2020

Updated: 21st January, 2020

Author: Gemma Marks

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The Bydureon Phase lll Trial: Supplementary Substudies

The Bydureon Phase lll Trial: Supplementary Substudies

The Cure Parkinson's Trust and the Van Andel Institute are delighted to be supporting two sub-studies led by Prof. Tom Foltynie within the important Bydureon phase lll trial... Read more

Published: 14th January, 2020

Updated: 29th July, 2020

Author: Suzanne Bailey

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2020 CPT Raid: Raid Alpine

2020 CPT Raid: Raid Alpine

This June 46 supporters of The Cure Parkinson’s Trust (CPT) will be taking on the next extreme cycling challenge in the CPT Raid series: the legendary Raid Alpine. Read more

Published: 14th January, 2020

Updated: 14th March, 2020

Author: Gemma Marks

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Ambroxol in Parkinson's: Results of Phase ll Trial Published

Ambroxol in Parkinson's: Results of Phase ll Trial Published

The Cure Parkinson's Trust (CPT) is delighted to announce the publication of the results of a Phase II clinical trial evaluating ambroxol as a potential treatment to slow the progression of Parkinson’s. Read more

Published: 13th January, 2020

Updated: 11th March, 2020

Author: Suzanne Bailey

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The Cure Parkinson's Trust - 15 Years

The Cure Parkinson's Trust - 15 Years

As we reach this milestone, we reflect on what we have achieved since the charity began in 2005 and look ahead to the plans we are shaping to mark this anniversary... Read more

Published: 9th January, 2020

Updated: 9th April, 2020

Author: Suzanne Bailey

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Review 2019: Research Highlights

Review 2019: Research Highlights

2019 was an exceptional year for The Cure Parkinson’s Trust, not only for raising further awareness of Parkinson’s but also for the breakthrough research we have supported. Find out more... Read more

Published: 6th January, 2020

Author: Suzanne Bailey

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CPT Mourns the Loss of Sir David Jones

CPT Mourns the Loss of Sir David Jones

Sir David Jones, Co-founder of The Cure Parkinson’s Trust (CPT), has died. Read more

Published: 31st December, 2019

Updated: 6th January, 2020

Author: Suzanne Bailey

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IPDGC 2019: London

IPDGC 2019: London

Over 150 researchers attended this two-day conference focused on improving our understanding of the genetics of Parkinson's, sponsored by The Cure Parkinson's Trust. Read more

Published: 19th December, 2019

Updated: 31st December, 2019

Author: Suzanne Bailey

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  • News
Clinical Trial for Anle138b

Clinical Trial for Anle138b

A drug, Anle138b, previously shown to rescue neurons in pre-clinical models of alpha synuclein-associated Parkinson's, is now being trialled in humans. Read more

Published: 19th December, 2019

Author: Suzanne Bailey

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  • News
GP2: Global Parkinson's Genetics Program

GP2: Global Parkinson's Genetics Program

Aligning Science Across Parkinson's (ASAP) was launched this year, with support from the Sergey Brin Family Foundation, and more recently ASAP announced the Global Parkinson's Genetics Program (GP2)... Read more

Published: 10th December, 2019

Updated: 14th January, 2020

Author: Suzanne Bailey

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  • News
Keeping Pace with LRRK2 and GCase

Keeping Pace with LRRK2 and GCase

New research from Northwestern University in Chicago suggests that rather than being targeted towards individuals with LRRK2- or GBA-associated Parkinson's, novel therapies in these fields may be beneficial for others in the wider Parkinson's affected community. Read more

Published: 10th December, 2019

Updated: 12th December, 2019

Author: Suzanne Bailey

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  • News
Accelerating Medicines Partnership for Parkinson’s - AMP-PD

Accelerating Medicines Partnership for Parkinson’s - AMP-PD

The US National Institute of Health (NIH) have recently announced the opening of a vast new data portal for Parkinson's research... Read more

Published: 25th November, 2019

Author: Suzanne Bailey

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  • News
Genetic Manipulators of Alpha Synuclein

Genetic Manipulators of Alpha Synuclein

A recently published study has identified a gene, DCLK1, as an important regulator of alpha synuclein in Parkinson's. Read more

Published: 25th November, 2019

Updated: 28th November, 2019

Author: Suzanne Bailey

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  • News
Ambroxol: Further Validation for Potential in Parkinson's

Ambroxol: Further Validation for Potential in Parkinson's

A recent study of brain tissue finds certain genetic factors strongly associated with the incidence of Parkinson's and gives further validation to one of our Linked Clinical trials - the Ambroxol trial in people with Parkinson's... Read more

Published: 20th November, 2019

Updated: 3rd February, 2020

Author: Suzanne Bailey

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  • News
Parkinson's Drug Trial Documentary Wins 'Best Science' Award

Parkinson's Drug Trial Documentary Wins 'Best Science' Award

'The Parkinson’s Drug Trial: A Miracle Cure?'  has won a Grierson Award for Best Science Documentary. The series aired in early 2019 and followed late CPT Co-founder Tom Isaacs and 8 other people through a pioneering drug delivery procedure... Read more

Published: 18th November, 2019

Updated: 14th January, 2020

Author: Suzanne Bailey

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  • News
Dr Heather Mortiboys and Dr Kevin McFarthing join CPT's Research Committee

Dr Heather Mortiboys and Dr Kevin McFarthing join CPT's Research Committee

The Cure Parkinson's Trust is pleased to announce two new additions to its Research Committee: Dr Heather Mortiboys and Dr Kevin McFarthing. Read more

Published: 12th November, 2019

Author: Gemma Marks

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  • News
Autumn Research Update Meeting 2019

Autumn Research Update Meeting 2019

Presentations from our Autumn Research Patient Update Meeting are now available to view. Read more

Published: 12th November, 2019

Updated: 28th November, 2019

Author: Gemma Marks

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  • News
Martin Wishart's Atlantic Sail for CPT

Martin Wishart's Atlantic Sail for CPT

To mark the 20th anniversary of running his Edinburgh restaurant, Scottish Michelin Star Chef Martin Wishart will be taking on the incredible challenge of sailing 3,500 miles across the Atlantic in a bid to raise awareness and funds for The Cure Parkinson’s Trust. Read more

Published: 11th November, 2019

Updated: 12th November, 2019

Author: Gemma Marks

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  • News
A New Enzyme to Inhibit LRRK2

A New Enzyme to Inhibit LRRK2

Researchers in Dundee and Stanford (USA) have identified a novel method of reducing the hyperactivity of the gene mutation in LRRK2, a major cause of familial and sporadic cases of Parkinson's... Read more

Published: 5th November, 2019

Updated: 28th November, 2019

Author: Suzanne Bailey

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  • News
The 2019 Tom Isaacs Charity Golf Day at Denham Golf Club

The 2019 Tom Isaacs Charity Golf Day at Denham Golf Club

The 2019 Tom Isaacs Charity Golf Day at Denham Golf Club saw 76 players enjoying a round of golf in memory of CPT’s late Co-founder and President, Tom Isaacs raising over £8,800 for CPT's pioneering Parkinson's research. Read more

Published: 21st October, 2019

Updated: 25th October, 2019

Author: Gemma Marks

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  • News
Another Ambroxol-like Drug for Treating Parkinson's?

Another Ambroxol-like Drug for Treating Parkinson's?

The findings of this new study suggest that enhancing cellular GCase activity with a drug similar to the now being repurposed drug Ambroxol in Parkinson's, may be beneficial to both people with genetic variants of Parkinson's and those with no obvious genetic influence... Read more

Published: 17th October, 2019

Updated: 6th January, 2020

Author: Suzanne Bailey

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  • News
Aligning Science Across Parkinson’s

Aligning Science Across Parkinson’s

The Milken Institute Center for Strategic Philanthropy and the Sergey Brin Family Foundation recently announced the launch of the Aligning Science Across Parkinson’s (ASAP) programme... Read more

Published: 16th October, 2019

Author: Suzanne Bailey

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  • News
Phase ll Clinical Trial to Explore Experimental K0706 in Early Parkinson's

Phase ll Clinical Trial to Explore Experimental K0706 in Early Parkinson's

Sun Pharma Advanced Research Company (SPARC) is conducting a Phase ll clinical trial (PROSEEK) to evaluate the safety and effectiveness of its experimental c-Abl inhibitor, K0706, in people with early Parkinson’s disease. Read more

Published: 14th October, 2019

Updated: 4th December, 2019

Author: Suzanne Bailey

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  • News
MIRO - A New Biomarker for Parkinson's?

MIRO - A New Biomarker for Parkinson's?

Researchers at Stanford University in the US looking for new biomarkers of Parkinson's, recently identified a protein called MIRO that in initial data very accurately identifies people with the condition... Read more

Published: 14th October, 2019

Author: Suzanne Bailey

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  • News
The Simvastatin Study Protocol

The Simvastatin Study Protocol

The Cure Parkinson's Trust (CPT) is co-funding the ongoing PD-STAT clinical trial evaluating the disease modifying potential of the cholesterol lowering drug simvastatin in Parkinson's within our Linked Clinical Trials programme. The trial protocol has recently been published... Read more

Published: 10th October, 2019

Updated: 28th November, 2019

Author: Suzanne Bailey

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  • News
The Bydureon Phase lll Trial

The Bydureon Phase lll Trial

The next phase of the Bydureon (exenatide-PD) clinical trial in Parkinson's has begun recruitment to determine, in a larger cohort, whether this diabetes treatment can slow down disease progression. Read more

Published: 10th October, 2019

Updated: 7th October, 2020

Author: Suzanne Bailey

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  • News
The Grouse & Grape Luncheon 2019

The Grouse & Grape Luncheon 2019

The ninth annual Grouse & Grape Luncheon was held on Tuesday 8 October at the historic Spencer House, and attracted 300 guests who raised over £35,000 for The Cure Parkinson’s Trust. Read more

Published: 9th October, 2019

Updated: 10th October, 2019

Author: Gemma Marks

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  • News
LRRK2 - Parkinson's, Leprosy, and Crohn’s

LRRK2 - Parkinson's, Leprosy, and Crohn’s

Researchers in Ottawa have announced a new discovery associated with the LRRK2 genetic form of Parkinson's... Read more

Published: 3rd October, 2019

Author: Suzanne Bailey

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  • News
'Voyager' Recruits Patients for Phase 2 Gene Therapy Delivery

'Voyager' Recruits Patients for Phase 2 Gene Therapy Delivery

Voyager Therapeutics announced it is recruiting participants for the company’s Phase ll trial of the VY-AADC02 gene therapy for Parkinson’s, enrolling in US... Read more

Published: 25th September, 2019

Updated: 28th November, 2019

Author: Jessica Wright

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  • News
New Research on the Importance of Exercise

New Research on the Importance of Exercise

This week, researchers at the Radboud University Medical Centre in Nijmegen (the Netherlands) published the results of a clinical trial evaluating an 'at home' high intensity exercise regime in people with Parkinson's, and they found that it had a positive effect. Read more

Published: 17th September, 2019

Updated: 25th September, 2019

Author: Gemma Marks

Related topics:
  • News
From Prostates to Parkinson's

From Prostates to Parkinson's

Chinese researchers in collaboration with scientists from the University of Iowa have today published new research suggesting that a drug, called Terazosin - which is used to treat enlarged prostates and high blood pressure - could be a useful drug to re-purpose for Parkinson's. Read more

Published: 17th September, 2019

Updated: 19th September, 2019

Author: Gemma Marks

Related topics:
  • News
Enterin Announce Clinical Trial Results

Enterin Announce Clinical Trial Results

Recently announced results from a clinical trial provide interesting support for a major theory about Parkinson's, and hope for individuals suffering from one of the common non-motor issues, constipation. Read more

Published: 10th September, 2019

Author: Gemma Marks

Related topics:
  • Research News
  • News
Microglia - Why They Are Important in the Parkinsonian Brain

Microglia - Why They Are Important in the Parkinsonian Brain

In this study, Prof. Brundin and his team demonstrate the importance of microglia (the immune cells in the brain) to the transfer of the Parkinson's-associated protein alpha synuclein in the brain. They suggested that pharmacological regulation of neuroinflammation could represent a future therapy for Parkinson's... Read more

Published: 28th August, 2019

Updated: 15th January, 2020

Author: Suzanne Bailey

Related topics:
  • News
The Linked Clinical Trials Meeting 2019

The Linked Clinical Trials Meeting 2019

The 2019 international Linked Clinical Trials meeting was held at the end of August in Grand Rapids, Michigan - this annual event is an important date in our calendar and heralds the process by which we are bringing much needed novel therapies for the Parkinson's into clinical trial as quickly as possible... Read more

Published: 20th August, 2019

Updated: 28th November, 2019

Author: Suzanne Bailey

Related topics:
  • News
The BRAIN Tapping Test Goes Mobile

The BRAIN Tapping Test Goes Mobile

Researchers at UCL have recently published a study validating a mobile device test which could continually monitor individuals with Parkinson's... Read more

Published: 15th August, 2019

Author: Suzanne Bailey

Related topics:
  • News
Bayer Buys Blue Rock

Bayer Buys Blue Rock

Bayer pharmaceutical has bought BlueRock Therapeutics which could have some important implications for the Parkinson's community... Read more

Published: 15th August, 2019

Author: Suzanne Bailey

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Latest

  • Raid Local 2021: Ventoux Local

    Raid Local 2021: Ventoux Local

    Join us on the 16th May for Raid Local 2021: Ventoux Local. Inspired by the infamous Club des Cinglés challenge to climb Mont Ventoux using 3 different routes in one day, riders will be training, planning and mapping to cover the equivalent distance and vertical ascent of 1, 2 or all 3 of those epic routes, all in one day, all on their local roads.

  • 3P - Post Doc Seminar - 21 January

    3P - Post Doc Seminar - 21 January

    Join the 3P Seminar on Thursday 21st January (12.00 EST), as Kyla Germain, PhD Candidate in Peter Kim’s lab at The Hospital for Sick Children (University of Toronto), and Tim König, Postdoctoral Researcher in Heidi McBride’s lab at Montreal Neurological Institute (McGill University), present their research.

  • Virtual Bridge Tournament

    Virtual Bridge Tournament

    The Cure Parkinson’s Trust (CPT) supporter Pam Willis will be holding her annual bridge tournament ‘virtually’ on 25 January in support of our pioneering Parkinson’s research and would love you to join her.

  • Virtual Bridge Tournament

    Virtual Bridge Tournament

    The Cure Parkinson’s Trust (CPT) supporter Pam Willis will be holding her annual bridge tournament ‘virtually’ on 25 January 2021 in support of our pioneering Parkinson’s research and would love you to join her.

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  • Breakthrough in stem cell treatment for Parkinson's

    In a major breakthrough for the treatment of Parkinson's, researchers working with laboratory rats show it is possible to make dopamine cells from embryonic stem cells and transplant them into the brain.

  • Tom Isaacs

    Tom Isaacs

    We are devastated to announce that Tom Isaacs, President and Co-founder of The Cure Parkinson’s Trust (CPT) died on Wednesday morning (31st May). Tom’s passing was unexpected and swift.

  • New Evidence Suggests Parkinson's Might Not Start in The Brain

    New Evidence Suggests Parkinson's Might Not Start in The Brain

    A new study adds to a raft of new evidence which suggests Parkinson's starts in the gut...

  • Science news

    Science news

    Read the latest Parkinson's science and research news here.

  • Trials - Repurposed Drugs

    Trials - Repurposed Drugs

    Our International Linked Clinical Trials initiative (iLCT) identifies potential new treatments to slow, stop or reverse Parkinson’s disease by 'repurposing' or repositioning drugs that are approved to treat other conditions.

  • Apply for Funding

    Apply for Funding

  • The NAC Trial - the facts

    The NAC Trial - the facts

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    Our story

  • Diabetes Drug Potential Disease-Modifying Therapy

    Diabetes Drug Potential Disease-Modifying Therapy

    The study, published in The Lancet and funded by The Michael J. Fox Foundation for Parkinson’s Research (MJFF), supported by CPT found that people with Parkinson’s treated with Exenatide for one year performed better in motor tests than those on placebo.

  • Alpha-synuclein and Parkinson's

    Alpha-synuclein and Parkinson's

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The Science of Parkinson's - Dr Simon Stott, Deputy Director of Research

The Science of Parkinson's - Dr Simon Stott, Deputy Director of Research

Read more

Published: 2nd March, 2015

Updated: 4th August, 2020

Author: Jessica Wright

Science news

Science news

Read the latest Parkinson's science and research news here. Read more

Published: 2nd March, 2015

Updated: 1st December, 2020

Author: Jessica Wright

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  • Projects and Progress
The Cure Collective

The Cure Collective

The Cure Collective is an opportunity to join like-minded individuals who are committed to help drive forward the quest to find a cure for Parkinson’s... Read more

Published: 3rd March, 2015

Updated: 28th July, 2020

Author: Jessica Wright

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  • Major gifts
Parkinson's Movement

Parkinson's Movement

Read more

Published: 3rd March, 2015

Updated: 6th July, 2020

Author:

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    20thJanuary, 2021 @CureParkinsonsT
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