New Evidence Suggests Parkinson's Might Not Start in The Brain - December 2016

A new study adds to a raft of new evidence which suggests Parkinson's starts in the gut.

'Gap' found in Brain's Firewall against Parkinson's - October 2016

An NIH-funded animal model study identifies a key player in the progression of Parkinson's.

Vaccine for Parkinson's Reports Positive Results from Boost Study - September 2016

New study results from Austrian biotech AFFiRiS support continued development of its vaccine against the key Parkinson's protein alpha-synuclein.

Diabetes Drug Focus of New Clinical Trial for Parkinson’s - September 2016

A clinical trial, part of our Linked Clinical Trials programme, is now underway at Cedars-Sinai in Los Angeles to investigate the use of the diabetes drug Liraglutide to slow or stop the progression of Parkinson's.

CPT Collaborates to Assess the Clinical Use of Nilotinib in Parkinson's - July 2016

The Michael J. Fox Foundation, Van Andel Research Institute and The Cure Parkinson’s Trust today announced plans to collaborate on the clinical development of nilotinib in preliminary studies as a treatment for Parkinson’s.

European Commission approves ONGENTYS® (opicapone)

BIAL announced today that its product ONGENTYS® (opicapone) for Parkinsons was approved by the European Commission. BIAL will make ONGENTYS® available for people with Parkinson’s across Europe in 2016 and 2017.

Blocking a Key Enzyme Stops Parkinson's Symptoms in Animal Model

Researchers at Johns Hopkins say they have gleaned two important new clues in the fight against Parkinson's: that blocking an enzyme called c-Abl prevents the disease in an animal model and that a chemical tag on a second protein may signal the disorder's presence and progression.

Researchers Open New Path of Discovery in Parkinson's Disease

Two genes associated with Parkinson's disease are key regulators of the immune system, providing direct evidence linking Parkinson's to autoimmune disease, a new study indicates.

Parkinson's Cell Transplants Show Good Reinnervation After 24 Years

A postmortem examination of a patient with Parkinson's who underwent dopaminergic cell transplantation 24 years ago has shown that the transplanted neurons had reinnervated the brain for all that time.

Are Stem Cell-Based Therapies for Parkinson’s Disease Ready for the Clinic in 2016?

A research paper recently published in the Journal of Parkinson's Disease discusses an impending clinical trial in Parkinson's disease (PD) using parthenogenetic stem cells for transplantation into PD patients.

World First Blood Test for Parkinson's

Researchers at La Trobe University Melbourne, Australia have developed a world-first diagnostic blood test which could change the lives of people with Parkinson's disease.

Our Research Update Meeting April 2016

At our recent research update meeting in April, Prof Roger Barker, Dr Mariah Lelos and CPT's Dr Richard Wyse presented their research news to a packed audience of Parkinson's advocates...

The Next Breakthrough Treatment for PD

Our survey conducted to mark World Parkinson’s Day 2016 of people living with Parkinson’s, clinicians and researchers, revealed that more than a third of responders chose 'drug repurposing' as the most likely source of a breakthrough in the treatment of the condition...

Regulating Neuronal Lipids Could Be Key in PD

Researchers have demonstrated that a decrease in polyunsaturated lipids in neuronal membranes, as seen in Parkinson's sufferers, directly affects the binding rate of dopamine and adenosine receptors...

The Critical Path Institute Supports Parkinson's

Seven of the world’s largest pharmaceutical companies have signed up to a ground-breaking consortium aimed at accelerating the development of safe and effective therapies for Parkinson’s...

Promising Respiratory Drug Focus of New Trial for Parkinson's

A medication approved to treat various respiratory diseases and that has demonstrated neuroprotective effects in preclinical studies is the focus of a new clinical trial for Parkinson’s disease...

The Toxicity of Iron in Neurones and Parkinson's

The link between iron and Parkinson's was known, but not how it actually brings on the condition. Recent important research has shown that an excess of iron in neurones impairs cellular recycling resulting in toxic oxidative stress...

Simvastatin Trial Underway

The cholesterol-lowering drug Simvastatin is to be trialled as a potential neuroprotective treatment for Parkinson’s. This country-wide trial part-funded by CPT and led by Plymouth University is now underway...

Stem Cell Therapies - Current Research Update

When diagnosed, people with Parkinson’s have often had the disease for years and have lost over half of the dopamine producing cells in their brain. Now scientists are searching for a way to replace these nerve cells...

Finding a Better Way in Clinical Trials

Fear about receiving the placebo is one of the biggest barriers to trial recruitment. In this article in Pharma Technology Focus, Tom Isaacs comments on new trial set ups which aim to reduce the number of people in the placebo groups and the progress being made...

Cancer Drug Effects Dramatic Improvements in Parkinson's

A cancer drug tested in a pilot study of 11 people with Parkinson’s has shown clinical improvements...

Nilotinib: Dr James Beck is Cautious but Hopeful

Dr James Beck from the Parkinson's Disease Foundation (PDF) comments on the recent news of an anti-cancer drug which has shown significant improvement of symptoms in Parkinson's patients...

Physical Therapy and Parkinson's

There have been reports recently in the media that suggest physiotherapy and occupational therapy do not help people with Parkinson's. CPT has a different view...